Author

M. Smelkinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

S. Ganesan· 2 shared A. Nita-Lazar· 1 shared B. Brown· 1 shared B. Jenkins· 1 shared C. Bradfield· 1 shared C. H. Coelho· 1 shared D. De Nardo· 1 shared E. Latz· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

S. Ganesan

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Author profile →

3 papers

Recent·Most cited

Human ESCRT-I and ALIX function as scaffolding helical filaments in vivo

S. J. Spada, K. M. Rose, P. Sette, S. K. O'Connor, V. B. Dussupt, V. S. Yerramilli, K. Nagashima, V. Helle Sjoelund, P. Cruz, J. Kabat, M. Smelkinson, S. Ganesan, A. Nita-Lazar, S. Scarlata, V. Hirsch, , F. Bouamr

This study shows ESCRT-I and ALIX form helical filaments in vivo, serving as structural scaffolds and ESCRT-III assembly templates for membrane scission and viral budding.

bioRxiv · May 1, 2024 · PreprintCell Biology

A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes

C. H. Coelho, W. K. Tang, M. Burkhardt, J. D. Galson, O. Muratova, N. Salinas, T. L. Alves e Silva, K. Reiter, N. MacDonald, V. Nguyen, M. Byrne-Steele, W. Pan, X. Hou, B. Brown, M. Eisenhower, , P. Duffy

The paper identifies a high-affinity human monoclonal antibody against Pfs230 that blocks oocyst formation in mosquitoes by targeting gamete surfaces.

bioRxiv · Sep 25, 2020 · PreprintImmunology

IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation

S. J. Vayttaden, M. Smelkinson, O. Ernst, R. J. Carlson, J. Sun, C. Bradfield, M. G. Dorrington, J. Liang, N. Bouladoux, R. A. Gottschalk, K.-S. Oh, G. Pegoraro, S. Ganesan, D. De Nardo, E. Latz, , I. D. C. Fraser

This study identifies IRAK1-mediated supramolecular organizing centers that coordinate multiple immune pathways to license inflammasome activation in response to microbial signals.

bioRxiv · Dec 26, 2019 · PreprintImmunology