Author

D. Fisch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. Clough· 3 shared E. Frickel· 2 shared V. Encheva· 2 shared A. Brandel· 1 shared A. Lehmann· 1 shared A. P. Snijders· 1 shared A. Shenoy· 1 shared A. Snijders· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

B. Clough

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

p97/VCP targets Toxoplasma gondii vacuoles for parasite restriction in interferon-stimulated human cells

B. Clough, D. Fisch, T. H. Mize, V. Encheva, A. Snijders, E. Frickel

This study identifies p97/VCP as an IFN-gamma-dependent host factor that restricts Toxoplasma gondii by acidifying the parasitophorous vacuole in multiple human cell types.

bioRxiv · Jun 20, 2023 · PreprintImmunology

Toxoplasma-proximal and distal control by GBPs in human macrophages

D. Fisch, B. Clough, R. T. Khan, L. Healy, E. Frickel

This study identifies GBP1, 2, and 5 roles in controlling Toxoplasma gondii infection in human macrophages, with GBP1 acting proximally and GBP2/5 distally.

bioRxiv · Aug 24, 2021Microbiology

The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa

A. Brandel, S. Aigal, S. Lagies, M. Schlimpert, A. Lehmann, D. Hummel, D. Fisch, A. V. Melendez, J. Madl, T. Eierhoff, B. Kammerer, W. Roemer

This study identifies CD59 and flotillins as key host proteins interacting with Pseudomonas aeruginosa's LecA, essential for bacterial invasion via a Gb3-enriched plasma membrane domain.

bioRxiv · Jun 26, 2020Cell Biology

Human GBP1 differentially targets Salmonella and Toxoplasma to license recognition of microbial ligands and caspase-mediateddeath

D. Fisch, B. Clough, M.-C. Domart, V. Encheva, H. Bando, A. P. Snijders, L. M. Collinson, M. Yamamoto, A. Shenoy, E.-M. Frickel

This study identifies GBP1's differential targeting of Salmonella and Toxoplasma to regulate caspase-mediated cell death and microbial ligand recognition.

bioRxiv · Apr 23, 2020Microbiology