Author

L. M. Collinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Assay:electronic health records· 2

Frequent Co-Authors

C. J. Peddie· 4 shared M. L. Jones· 4 shared A. P. Snijders· 3 shared A. E. Weston· 2 shared C. C. Reyes-Aldasoro· 2 shared C. Karabag· 2 shared M. J. Blackman· 2 shared M. R. Russell· 2 shared

Activity by Year

2020-2023 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersCell Biology

C. J. Peddie

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy

D. Krentzel, M. Elphick, M.-C. Domart, C. J. Peddie, R. F. Laine, C. Shand, R. Henriques, L. M. Collinson, M. L. Jones

CLEM-Reg automates 3D alignment of vCLEM datasets, achieving sub-micron correlation of fluorescent signals with EM structures and enabling identification of TGN46-positive transport carriers.

bioRxiv · May 11, 2023Cell Biology

Global analysis of putative phospholipases in the malaria parasite Plasmodium falciparum reveals critical factors for parasite proliferation

P.-C. Burda, A. Ramaprasad, E. Pietsch, S. Bielfeld, C. Söhnchen, L. Wilcke, J. Strauss, D. Schwudke, A. Sait, L. M. Collinson, M. J. Blackman, T.-W. Gilberger

The paper identifies essential phospholipases in Plasmodium falciparum, showing PF3D7_1013500 is critical for parasite maturation and PF3D7_1358000 is vital for mitochondrial function and growth.

bioRxiv · Jun 28, 2021 · PreprintMicrobiology

Citizen science, cells and CNNs - deep learning for automatic segmentation of the nuclear envelope in electron microscopy data, trained with volunteer segmentations

H. Spiers, H. Songhurst, L. Nightingale, J. de Folter, R. Hutchings, C. J. Peddie, A. Weston, A. Strange, S. Hindmarsh, C. Lintott, L. M. Collinson, M. L. Jones

This paper trains a deep learning model to automatically segment the nuclear envelope in electron microscopy data using volunteer annotations from a citizen science project.

bioRxiv · Jul 28, 2020Cell Biology

The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

C. R. Collins, F. Hackett, S. A. Howell, A. P. Snijders, M. R. Russell, L. M. Collinson, M. J. Blackman

This study shows that the malaria parasite's SUB2 protease is essential for shedding surface proteins during RBC invasion and for sealing the host cell membrane.

bioRxiv · Jul 15, 2020Microbiology

Human GBP1 differentially targets Salmonella and Toxoplasma to license recognition of microbial ligands and caspase-mediateddeath

D. Fisch, B. Clough, M.-C. Domart, V. Encheva, H. Bando, A. P. Snijders, L. M. Collinson, M. Yamamoto, A. Shenoy, E.-M. Frickel

This study identifies GBP1's differential targeting of Salmonella and Toxoplasma to regulate caspase-mediated cell death and microbial ligand recognition.

bioRxiv · Apr 23, 2020Microbiology

Differential protein phosphorylation affects the localisation of two secreted Toxoplasma proteins and is widespread during stage conversion

J. Young, M. Broncel, H. Teague, M. R. Russell, O. McGovern, M. Renshaw, D. Frith, A. P. Snijders, L. M. Collinson, V. B. Carruthers, S. E. Ewald, M. Treeck

This paper investigates the role of phosphorylation in regulating the localization of two secreted Toxoplasma proteins during stage conversion and identifies widespread differential phosphorylation of secreted proteins.

bioRxiv · Apr 9, 2020 · PreprintMicrobiology

Geometric differences between nuclear envelopes of Wild-type and Chlamydia trachomatis-infected HeLa cells

C. Karabag, M. L. Jones, C. J. Peddie, A. E. Weston, L. M. Collinson, C. C. Reyes-Aldasoro

The paper compares geometric features of nuclear envelopes in wild-type and Chlamydia trachomatis-infected HeLa cells using electron microscopy and spheroid modeling.

bioRxiv · Apr 2, 2020 · PreprintCell Biology

Semantic Segmentation of HeLa Cells: An Objective Comparison between one Traditional Algorithm and Three Deep-Learning Architectures

C. Karabag, M. L. Jones, C. J. Peddie, A. E. Weston, L. M. Collinson, C. C. Reyes-Aldasoro

This paper compares a traditional image-processing algorithm with three deep learning models for semantic segmentation of HeLa cells, finding the traditional method outperforms all deep learning architectures.

bioRxiv · Mar 5, 2020Cancer Biology