Author

D. Ogasawara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

B. Cravatt· 2 shared B. Melillo· 2 shared E. Njomen· 2 shared H. Li· 2 shared K. DeMeester· 2 shared S. J. Won· 2 shared S. Schreiber· 2 shared A. Gurkan Ozer· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

B. Cravatt

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Author profile →

3 papers

Recent·Most cited

Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes

D. Ogasawara, D. Konrad, Z. Y. Tan, K. Carey, J. Luo, S. J. Won, H. Li, T. Carter, K. DeMeester, E. Njomen, S. Schreiber, R. Xavier, B. Melillo, B. Cravatt

The paper introduces photo-stereoprobes for expanding the ligandable proteome and demonstrates their use in discovering bioactive small molecules.

bioRxiv · Feb 27, 2024Biochemistry

Stimulatory effect of monoacylglycerol lipase inhibitor MJN110 on locomotion and step kinematics demonstrated by high-precision 3D motion capture in mice

B. M. Ignatowska-Jankowska, A. Gurkan Ozer, A. Kuck, M. J. Niphakis, D. Ogasawara, B. F. Cravatt, M. Y. Uusisaari

This study shows that inhibiting monoacylglycerol lipase (MJN110) enhances locomotion and step kinematics in mice, while inhibiting fatty acid amide hydrolase (PF3845) suppresses it, revealing distinct effects of endocannabinoid pathway manipulations on motor behavior.

bioRxiv · Jun 25, 2023 · PreprintAnimal Behavior & Cognition

Proteomic discovery of chemical probes that perturb protein complexes in human cells

M. Lazear, J. Remsberg, M. Jaeger, K. Rothamel, H.-l. Her, K. DeMeester, E. Njomen, S. Hogg, J. Rahman, L. Whitby, S. J. Won, M. Schafroth, D. Ogasawara, M. Yokoyama, G. Lindsey, , B. Cravatt

This study develops a proteomic strategy to identify chemical probes that perturb protein complexes in human cells by analyzing electrophilic compounds' effects on protein interactions.

bioRxiv · Dec 12, 2022Biochemistry