Author

D. M. Barrett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. A. Grupp· 2 shared A. C. Resnick· 1 shared A. Felmeister· 1 shared A. Stern· 1 shared C. Brimley· 1 shared C. Burudpakdee· 1 shared C. Chen· 1 shared C. Griffin· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

S. A. Grupp

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

J. B. Foster, C. Griffin, J. L. Rokita, A. Stern, C. Brimley, K. Rathi, M. V. Lane, S. N. Buongervino, T. Smith, P. J. Madsen, D. Martinez, R. Wechsler-Reya, K. Kariko, P. B. Storm, D. M. Barrett, , K. R. Bosse

This study develops mRNA chimeric antigen receptor T cells targeting GPC2 on pediatric brain tumors, showing significant tumor regression and prolonged survival without toxicity.

bioRxiv · Jul 6, 2021Cancer Biology

Distinct bioenergetic features of human invariant natural killer T (iNKT) cells enable retained functions in nutrient-deprived states

P. Khurana, C. Burudpakdee, S. A. Grupp, U. H. Beier, D. M. Barrett, H. Bassiri

This study identifies distinct bioenergetic features of human iNKT cells that enable their survival and effector function in nutrient-deprived conditions compared to conventional T cells.

bioRxiv · Apr 29, 2021Immunology

Single-cell antigen-specific activation landscape of CAR T infusion product identifies determinants of CD19 positive relapse in patients with ALL

Z. Bai, S. Woodhouse, D. Kim, S. Lundh, H. Sun, Y. Deng, Y. Xiao, D. M. Barrett, R. M. Myers, S. A. Grupp, C. H. June, J. J. J. Joseph Melenhorst, P. G. Camara, R. Fan

The paper analyzes single-cell data from CAR T infusion products to identify factors associated with CD19-positive relapse in ALL patients.

bioRxiv · Apr 15, 2021Immunology

Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia

C. Chen, W. Yu, F. Alikarami, Q. Qiu, C.-h. Chen, J. Flournoy, P. Gao, Y. Uzun, L. Fang, Y. Yu, Q. Zhu, K. Wang, C. Libbrecht, A. Felmeister, I. Rozich, , K. Tan

This study uses single-cell multi-omics to identify lineage plasticity and stem-cell-like blasts in KMT2A-rearranged leukemia, linking these features to poor prognosis in infants.

bioRxiv · Dec 6, 2020 · PreprintCancer Biology