Author

K. R. Bosse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2

Frequent Co-Authors

J. L. Rokita· 3 shared J. M. Maris· 3 shared D. Martinez· 2 shared K. S. Rathi· 2 shared M. V. Lane· 2 shared A. B. Radaoui· 1 shared A. C. Resnick· 1 shared A. Delaidelli· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCancer Biology

J. L. Rokita

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Author profile →

4 papers

Recent·Most cited

Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma

J. G. M. Strijker, G. Pascual-Pasto, Y. J. Kalmeijer, E. Kalaitsidou, C. Zhao, B. McIntyre, S. Matlaga, L. L. Visser, M. Barisa, C. Himsworth, R. Shah, H. Muller, L. G. Schild, P. G. Hains, Q. Zhong, , J. Wienke

This study identifies MIF as a key immunosuppressive factor in neuroblastoma that inhibits CAR T-cell efficacy, showing that blocking MIF enhances T-cell activation and therapeutic potential.

bioRxiv · Apr 5, 2024Cancer Biology

A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma

A. K. Weiner, A. B. Radaoui, M. Tsang, D. Martinez, S. Sidoli, K. L. Conkrite, A. Delaidelli, A. Modi, J. L. Rokita, K. Patel, M. V. Lane, B. Zhang, C. Zhong, B. Ennis, D. P. Miller, , S. J. Diskin

This study identifies DLK1 as a potential immunotherapeutic target in neuroblastoma through integrative proteomic, transcriptomic, and epigenomic analysis.

bioRxiv · Dec 6, 2023 · PreprintCancer Biology

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

J. B. Foster, C. Griffin, J. L. Rokita, A. Stern, C. Brimley, K. Rathi, M. V. Lane, S. N. Buongervino, T. Smith, P. J. Madsen, D. Martinez, R. Wechsler-Reya, K. Kariko, P. B. Storm, D. M. Barrett, , K. R. Bosse

This study develops mRNA chimeric antigen receptor T cells targeting GPC2 on pediatric brain tumors, showing significant tumor regression and prolonged survival without toxicity.

bioRxiv · Jul 6, 2021Cancer Biology

LIN28B-PDZ Binding Kinase Signaling Promotes Neuroblastoma Metastasis

D. Chen, J. Cox, J. Annam, M. Weingart, G. Essien, K. S. Rathi, J. L. Rokita, P. Khurana, S. M. Cuya, K. R. Bosse, A. Pilgrim, D. Li, J. M. Maris, R. W. Schnepp

This study identifies LIN28B's role in promoting neuroblastoma metastasis through the regulation of PBK, a kinase that enhances self-renewal and migration.

bioRxiv · Aug 21, 2019Cancer Biology