Author

D. M. Gilkes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1

Frequent Co-Authors

A. Nukovic· 1 shared B. M. Woolston· 1 shared C. T. Taylor· 1 shared D. Samanta· 1 shared F. Kurtoglu· 1 shared G. L. Semenza· 1 shared G. Zhou· 1 shared H. L. Rocha· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. Nukovic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Controlling pericellular oxygen tension in cell culture reveals distinct breast cancer responses to low oxygen tensions

Z. J. Rogers, T. C. Colombani, S. Khan, K. Bhatt, A. Nukovic, G. Zhou, B. M. Woolston, C. T. Taylor, D. M. Gilkes, N. Slavov, S. A. Bencherif

This study shows that controlling incubator gas phase O2 is insufficient to control pericellular O2 in cell culture, revealing non-monotonic breast cancer responses to low O2.

bioRxiv · Oct 2, 2023Bioengineering

Enrichment of breast cancer stem cells following cytotoxic chemotherapy is mediated by hypoxia-inducible factors

D. Samanta, D. M. Gilkes, L. Xiang, P. Chaturvedi, G. L. Semenza

This study shows that cytotoxic chemotherapy in TNBC increases BCSCs via HIFs, leading to relapse, and that HIF inhibitors can block this effect.

bioRxiv · Jun 27, 2022 · PreprintCancer Biology

A persistent invasive phenotype in post-hypoxic tumor cells is revealed by novel fate-mapping and computational modeling

H. L. Rocha, I. Godet, F. Kurtoglu, J. Metzcar, K. Konstantinopoulos, S. Bhoyar, D. M. Gilkes, P. Macklin

The paper uses fate-mapping and computational modeling to show that post-hypoxic tumor cells develop an invasive phenotype that promotes tumor expansion into oxygenated regions.

bioRxiv · Dec 30, 2020Cancer Biology