Author

D. M. Pelt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:deep learning· 2 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. BriegeliD· 1 shared A. Latka· 1 shared A. Otwinowska· 1 shared A. R. Costa· 1 shared C. K. Cassidy· 1 shared C. Y. Kim· 1 shared E. S. Egan· 1 shared J. A. Sethian· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. BriegelORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

High resolution reconstruction of a Jumbo bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

R. Ouyang, A. R. Costa, C. K. Cassidy, A. Otwinowska, V. C. J. Williams, A. Latka, P. J. Stansfeld, Z. J. Drulis-Kawa, Y. Briers, D. M. Pelt, S. J. J. Brouns, A. Briegel

This study determines the high-resolution structure of a jumbo bacteriophage infecting Klebsiella pneumoniae, revealing its complex tail fibers that enable infection of multiple capsular polysaccharide types.

Nature Communications · Nov 24, 2022Peer-reviewedMicrobiology

Coupling cryo-electron tomography with mixed-scale dense neural networks reveals re-organization of the invasion machinery of Toxoplasma gondii upon ionophore-stimulation

L.-a. Segev-Zarko, P. D. Dahlberg, S. Y. Sun, D. M. Pelt, C. Y. Kim, E. S. Egan, J. A. Sethian, W. Chiu, J. C. Boothroyd

The paper uses cryo-electron tomography and mixed-scale dense neural networks to analyze the reorganization of Toxoplasma gondii's invasion machinery upon ionophore stimulation, revealing structural changes and evolutionary conservation with Plasmodium falciparum.

PNAS Nexus · Sep 1, 2022Peer-reviewedCell Biology