Author

D. Muliaditan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

R. DasGupta· 2 shared A. Caplin· 1 shared A. W. C. Pang· 1 shared B. Chowdhury· 1 shared C. Coruh· 1 shared C. E. L. Chua· 1 shared C. Green· 1 shared D. Bowtell· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

R. DasGupta

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3 papers

Recent·Most cited

Deciphering the function of intrinsic and genomics-driven epigenetic heterogeneity in head and neck cancer progression with single-nucleus CUT&RUN

H. Womerley, D. Muliaditan, R. DasGupta, L. F. Cheow

This study develops a single-nucleus CUT&RUN assay to analyze histone modifications in HNSCC cell lines, revealing how epigenetic changes contribute to cancer progression and heterogeneity.

bioRxiv · Feb 14, 2024 · PreprintCancer Biology

Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

S. R. Dehkordi, I. T.-L. Wong, J. Ni, J. Luebeck, K. Zhu, G. Prasad, L. Krockenberger, G. Xu, B. Chowdhury, U. Rajkumar, A. Caplin, D. Muliaditan, C. Coruh, Q. Jin, K. Turner, , V. Bafna

The paper introduces OM2BFB, an algorithm detecting BFB amplifications using OGMs, showing high precision and recall, and finds BFB events are common in certain cancers but not linked to intratumoral heterogeneity or rapid genome change.

bioRxiv · Dec 12, 2023 · PreprintCancer Biology

Mechanisms of Chromosomal Instability in High-grade Serous Ovarian Carcinoma.

N. Tamura, N. Shaikh, D. Muliaditan, J. McGuinness, D. Moralli, M.-A. Durin, C. Green, D. Bowtell, F. Balkwill, K. Curtius, S. McClelland

This study identifies multiple co-existing mechanisms driving chromosomal instability in high-grade serous ovarian carcinoma using functional assays and cell line models.

bioRxiv · Aug 6, 2019Cancer Biology