C. Green

Structures of muscle-type nicotinic acetylcholine receptor with α-conotoxins reveal determinants of receptor-subtype specificity

The paper determines the molecular basis of -conotoxin specificity for muscle-type nAChRs using cryo-EM structures and computational methods.

Individual dietary amino acid restrictions induce distinct metabolic and chromatin states

The paper investigates how dietary restriction of specific essential amino acids affects metabolism and chromatin states in mice, finding distinct effects for methionine, leucine, and isoleucine.

Females translate male mRNA transferred during mating

The paper investigates whether RNA from Drosophila male seminal fluid is translated by females, identifying 67 male-derived, female-translated proteins and their roles in postmating interactions.

Symptomatic fever management in children A systematic review of national and international guidelines

This study reviews fever management guidelines for children, finding inconsistent recommendations and low evidence levels for antipyresis thresholds.

C. elegans pharyngeal pumping provides a whole organism bio-assay to investigate anti-cholinesterase intoxication and antidotes

This paper uses C. elegans pharyngeal pumping as a bio-assay to study anti-cholinesterase intoxication and antidote efficacy.

Autophagy in T cells from aged donors is maintained by spermidine, and correlates with function and vaccine responses

This study shows that spermidine maintains autophagy in aged human T cells, improving vaccine responses by enhancing IFN-gamma secretion and T cell function.

Mechanisms of Chromosomal Instability in High-grade Serous Ovarian Carcinoma.

This study identifies multiple co-existing mechanisms driving chromosomal instability in high-grade serous ovarian carcinoma using functional assays and cell line models.