M. Yokoyama

SLC26A2-mediated sulfate metabolism is essential for the tooth development

This study shows that SLC26A2-mediated sulfate metabolism is essential for tooth development, as its deficiency leads to craniofacial abnormalities and tooth hypoplasia in mice.

Proteomic discovery of chemical probes that perturb protein complexes in human cells

This study develops a proteomic strategy to identify chemical probes that perturb protein complexes in human cells by analyzing electrophilic compounds' effects on protein interactions.

Extension of bacterial rDNA sequencing to concurrent epigenetic analysis and its application to 16S meta-epigenetics

This paper introduces an add-on method to 16S rDNA sequencing for concurrent DNA methylation analysis, identifying novel methylation sites and a methyltransferase in Morganella morganii.

Microtubule Defect Involved in 'Mitophagy Resistance' Under Subacute Oxidative Stress - Potential Mechanism for Cellular Inflammation

This study investigates how oxidative stress impairs mitophagy by disrupting microtubule networks and shows that trehalose can restore microtubule function and improve mitophagy.

Dynamic rotation of the protruding domain enhances the infectivity of norovirus

This study shows that the protruding domain of norovirus capsids dynamically rotates between rising and resting conformations in response to pH and metal ions, enhancing infection efficiency.

Logistic Regression Analysis of Multiple Interosseous Hand-Muscle Activities using Surface Electromyography during Finger-Oriented Tasks

This study uses logistic regression to analyze surface EMG signals from hand muscles during finger tasks, finding better performance with frequency-domain variables in multivariate models.

Hidden antibiotic resistance fitness costs revealed by GWAS-based epistasis analysis

The paper identifies hidden fitness costs of mupirocin resistance in Staphylococcus aureus using GWAS and proteomics, revealing pleiotropic effects on toxin production and virulence.