Author

D. R. Boutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

J. D. Gollihar· 3 shared A. Annapareddy· 2 shared A. P. Horton· 2 shared C.-W. Chou· 2 shared I. J. Finkelstein· 2 shared J. Goike· 2 shared K. Javanmardi· 2 shared W. N. Voss· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

J. D. Gollihar

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3 papers

Recent·Most cited

Antibody escape and cryptic cross-domain stabilization in the SARS CoV-2 Omicron spike protein

K. Javanmardi, T. H. Segall-Shapiro, C.-W. Chou, D. R. Boutz, R. J. Olsen, X. Xie, H. Xia, P.-Y. Shi, C. D. Johnson, A. Annapareddy, S. Weaver, J. M. Musser, A. D. Ellington, I. J. Finkelstein, J. D. Gollihar

This study examines the molecular effects of Omicron spike mutations on ACE2 binding and antibody escape, revealing compensatory stabilizing mutations that enable high mutation counts.

bioRxiv · Apr 18, 2022Immunology

Rapid characterization of spike variants via mammalian cell surface display

K. Javanmardi, C.-W. Chou, C. I. Terrace, A. Annapareddy, T. S. Kaoud, Q. Guo, J. Lutgens, H. Zorkic, A. P. Horton, E. C. Gardner, G. Nguyen, D. R. Boutz, J. Goike, W. N. Voss, H.-C. Kuo, , I. J. Finkelstein

This study characterizes SARS-CoV-2 spike variants by assessing their expression, ACE2 binding, and neutralizing antibody recognition across multiple variants.

bioRxiv · Mar 30, 2021Biochemistry

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

W. N. Voss, Y. J. Hou, N. V. Johnson, J. E. Kim, G. Delidakis, A. P. Horton, F. Bartzoka, C. J. Paresi, Y. Tanno, S. A. Abbasi, W. Pickens, K. George, D. R. Boutz, D. M. Towers, J. R. McDaniel, , G. C. Ippolito

The paper identifies prevalent, protective, and convergent IgG antibodies targeting non-RBD epitopes of SARS-CoV-2 spike protein in convalescent plasma.

bioRxiv · Dec 20, 2020Immunology