Author

G. Nguyen

European Bioinformatics Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Biophysics· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

H.-C. Kuo· 2 shared I. J. Finkelstein· 2 shared A. Annapareddy· 1 shared A. Guyer· 1 shared A. M. Berry· 1 shared A. Mazzagatti· 1 shared A. P. Horton· 1 shared B. Wills· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

H.-C. Kuo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mitotic clustering of pulverized chromosomes from micronuclei

Y.-F. Lin, J. E. Valle-Inclan, A. Mazzagatti, Q. Hu, E. G. Maurais, A. Guyer, J. T. Sanders, J. Engel, G. Nguyen, D. Bronder, S. F. Bakhoum, I. Cortes-Ciriano, P. Ly

This study shows that acentric chromosome fragments from micronuclei cluster during mitosis, leading to biased inheritance and balanced chromothripsis in cancer.

Nature · Jun 29, 2023Peer-reviewedCell Biology

MRN and Topoisomerase IIIα-RMI1/2 synchronize DNA resection motor proteins

M. M. Soniat, G. Nguyen, H.-C. Kuo, I. J. Finkelstein

This study uses single-molecule imaging to show how MRN and TOP3A-RMI1/2 coordinate with BLM and DNA2 to efficiently resect DNA during homologous recombination.

bioRxiv · Jul 1, 2022 · PreprintBiophysics

Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes

Martin Hunt, Brice Letcher, Kerri M. Malone, G. Nguyen, Michael B. Hall, Rachel Colquhoun, Leandro Lima, Michael C. Schatz, Srividya Ramakrishnan, Zamin Iqbal

Minos integrates variant calls from multiple tools to adjudicate discrepancies and jointly genotype bacterial cohorts, improving accuracy in detecting SNPs and indels.

bioRxiv · Sep 15, 2021 · PreprintBioinformatics

Rapid characterization of spike variants via mammalian cell surface display

K. Javanmardi, C.-W. Chou, C. I. Terrace, A. Annapareddy, T. S. Kaoud, Q. Guo, J. Lutgens, H. Zorkic, A. P. Horton, E. C. Gardner, G. Nguyen, D. R. Boutz, J. Goike, W. N. Voss, H.-C. Kuo, , I. J. Finkelstein

This study characterizes SARS-CoV-2 spike variants by assessing their expression, ACE2 binding, and neutralizing antibody recognition across multiple variants.

bioRxiv · Mar 30, 2021Biochemistry

A human ex vivo dengue virus neutralization assay identifies priority antibodies and epitopes for vaccines and therapeutics.

T. Vu, H. Clapham, V. Huynh, L. Vo, D. Le, N. Vu, G. Nguyen, T. Huynh, K. Duong, V. Tran, H. Huynh, T. Huynh, T. Nguyen, N. Nguyen, T. Luong, , C. Simmons

This study develops an ex vivo dengue virus neutralization assay using mosquitoes to identify potent human monoclonal antibodies and their epitopes for vaccine and therapeutic development.

bioRxiv · Jan 10, 2019Immunology

Stable Genetic Transformation and Heterologous Expression in the Nitrogen-fixing Plant Endosymbiont Frankia alni ACN14a

I. Gifford, S. Vance, G. Nguyen, A. M. Berry

This paper establishes a stable genetic transformation system for Frankia alni ACN14a, enabling gene expression analysis and differentiation between hyphae and nitrogen-fixing vesicles under nitrogen limitation.

bioRxiv · Dec 14, 2018Microbiology