Author

D. R. Heintzman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. K. Mangalam· 1 shared A. M. Cameron· 1 shared A. Sugiura· 1 shared B. F. Eichman· 1 shared B. H. Greer· 1 shared C. Sanders· 1 shared D. L. Greenwood· 1 shared G. Andrejeva· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. K. Mangalam

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Author profile →

3 papers

Recent·Most cited

RTEL1 and MCM10 overcome topological stress during vertebrate replication termination

L. V. Campos, B. H. Greer, D. R. Heintzman, T. Kavlashvili, W. H. McDonald, K. L. Rose, B. F. Eichman, J. M. Dewar

The paper identifies RTEL1 and MCM10 as proteins that help replication forks overcome topological stress during DNA synthesis termination in Xenopus egg extracts.

bioRxiv · Jan 27, 2022Biochemistry

MTHFD2 is a Metabolic Checkpoint Controlling Effector and Regulatory T Cell Fate and Function

A. Sugiura, G. Andrejeva, K. Voss, D. R. Heintzman, K. L. Beier, M. M. Wolf, D. L. Greenwood, X. Ye, S. K. Shahi, S. N. Freedman, A. M. Cameron, P. Foerch, T. Bourne, X. Xu, J. C. Garcia-Canaveras, , J. Rathmell

This study identifies MTHFD2 as a metabolic checkpoint that regulates T cell fate and function by promoting effector cells and suppressing regulatory T cells.

bioRxiv · Feb 3, 2021Immunology

Glycosylation Limits Forward Trafficking of the Tetraspan Membrane Protein PMP22

J. T. Marinko, M. T. Wright, D. R. Heintzman, L. Plate, C. Sanders

The paper shows that N-linked glycosylation limits PMP22 cell surface trafficking and identifies key quality control factors in its biogenesis.

bioRxiv · Dec 18, 2020Cell Biology