Virus-Dependent Immune Conditioning of Tissue Microenvironments
S. Jiang, C. N. Chan, X. Rovira-Clave, H. Chen, Y. Bai, B. Zhu, E. McCaffrey, N. F. Greenwald, C. Liu, G. L. Barlow, J. L. Weirather, K. Busman-Sahay, M. Nekorchuk, M. Terry, S. Younger, , G. P. Nolan
The paper develops PANINI-MIBI to analyze DNA, RNA, and protein in SIV-infected tissues, revealing IL10 upregulation and macrophage polarization linked to viral latency.
bioRxiv · May 21, 2021Immunology