Author

N. F. Greenwald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 6 Organism:human· 5 Research Focus:spatial domain detection· 5 Approach:experimental assay· 3 Assay:imaging· 3 Approach:microscopy & imaging analysis· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2

Frequent Co-Authors

M. Angelo· 6 shared A. Baranski· 3 shared E. F. McCaffrey· 3 shared S. C. Bendall· 3 shared D. R. Glass· 2 shared E. McCaffrey· 2 shared L. Keren· 2 shared M. Bosse· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersImmunology

M. Angelo

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity

K. E. Houlahan, A. Khan, N. F. Greenwald, R. B. West, M. Angelo, C. Curtis

This study shows germline variants influence somatic evolution in breast cancer by modulating immunoediting, affecting tumor subtype and metastatic potential.

bioRxiv · Mar 15, 2023 · PreprintCancer Biology

Single-Cell Imaging Maps Inflammatory Cell Subsets to Pulmonary Arterial Hypertension Vasculopathy

S. Ferrian, A. Cao, E. F. McCaffrey, T. Saito, N. F. Greenwald, M. R. Nicolls, T. Bruce, R. T. Zamanian, P. A. Del Rosario, M. Rabinovitch, M. Angelo

The paper maps immune cell subsets in PAH lungs using MIBI-TOF, identifying mo-DCs and their role in vascular remodeling and linking immune dysregulation to disease severity in HPAH.

bioRxiv · Dec 3, 2022Immunology

Virus-Dependent Immune Conditioning of Tissue Microenvironments

S. Jiang, C. N. Chan, X. Rovira-Clave, H. Chen, Y. Bai, B. Zhu, E. McCaffrey, N. F. Greenwald, C. Liu, G. L. Barlow, J. L. Weirather, K. Busman-Sahay, M. Nekorchuk, M. Terry, S. Younger, , G. P. Nolan

The paper develops PANINI-MIBI to analyze DNA, RNA, and protein in SIV-infected tissues, revealing IL10 upregulation and macrophage polarization linked to viral latency.

bioRxiv · May 21, 2021Immunology

Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma

T. Risom, D. R. Glass, C. C. Liu, B. Rivero-Gutierrez, A. Baranski, E. F. McCaffrey, N. F. Greenwald, A. C. Kagel, S. H. Strand, S. Varma, A. Kong, L. Keren, S. Srivastava, C. Zhu, Z. Khair, , M. Angelo

The paper analyzes tumor microenvironment changes from normal to invasive breast cancer using imaging and machine learning, finding coordinated shifts in stromal cell location and function.

bioRxiv · Jan 5, 2021Cancer Biology

Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood

E. F. McCaffrey, M. Donato, L. Keren, Z. Chen, M. Fitzpatrick, V. Jojic, A. Delmastro, N. F. Greenwald, A. Baranski, W. Graf, M. Bosse, P. K. Ramdial, E. Forgo, D. Van Valen, M. van de Rijn, , M. Angelo

This study uses multiplexed imaging and transcriptomics to identify immunosuppressive features in TB granulomas and blood, linking local and systemic immune responses.

bioRxiv · Jun 8, 2020 · PreprintImmunology

Multiplexed Single-cell Metabolic Profiles Organize the Spectrum of Human Cytotoxic T Cells

F. J. Hartmann, D. Mrdjen, E. McCaffrey, D. R. Glass, N. F. Greenwald, A. Bharadwaj, Z. Khair, A. Baranski, R. Baskar, M. Angelo, S. C. Bendall

This study maps metabolic profiles of human cytotoxic T cells using single-cell technologies, revealing tissue-specific metabolic states and spatial metabolic neighborhoods in colorectal carcinoma.

bioRxiv · Jan 17, 2020 · PreprintImmunology

Patient-derived xenografts undergo murine-specific tumor evolution

U. Ben-David, G. Ha, Y.-Y. Tseng, N. F. Greenwald, C. Oh, J. Shih, J. M. McFarland, B. Wong, J. S. Boehm, R. Beroukhim, T. R. Golub

This study shows that PDX tumors acquire new genomic changes over passages, differ from human tumors, and affect drug responses.

bioRxiv · Jul 24, 2017Cancer Biology