Author

D. R. Zollinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. M. Beechem· 2 shared M. S. Cuoco· 2 shared O. Cohen· 2 shared A. B. Haynes· 1 shared A. Bejnood· 1 shared A. Kanodia· 1 shared A. M. Magnuson· 1 shared A. R. Richman· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

J. M. Beechem

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Author profile →

3 papers

Recent·Most cited

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

K. Pelka, M. Hofree, J. Chen, S. Sarkizova, J. D. Pirl, V. Jorgji, A. Bejnood, D. Dionne, W. H. Ge, K. H. Xu, S. X. Chao, D. R. Zollinger, D. J. Lieb, J. W. Reeves, C. A. Fuhrman, , J

The paper identifies immune hubs in colorectal cancer by analyzing transcriptional and spatial patterns in MMRd and MMRp tumors.

bioRxiv · Jan 30, 2021 · PreprintCancer Biology

Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma

L. Jerby, C. Neftel, M. E. Shore, M. J. McBride, B. Haas, B. Izar, H. R. Weissman, A. Volorio, G. Boulay, L. Cironi, A. R. Richman, L. C. Broye, J. M. Gurski, C. C. Luo, R. Mylvaganam, , A. Regev

The paper profiles synovial sarcoma tumors to show that the SS18-SSX fusion drives oncogenic programs, which are repressed by immune cells and can be targeted with HDAC and CDK4/6 inhibitors.

bioRxiv · Aug 4, 2019 · PreprintCancer Biology

High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

C. R. Merritt, G. T. Ong, S. Church, K. Barker, G. Geiss, M. Hoang, J. Jung, Y. Liang, J. McKay-Fleisch, K. Nguyen, K. Sorg, I. Sprague, C. Warren, S. Warren, Z. Zhou, , J. M. Beechem

This paper introduces Digital Spatial Profiling (DSP), a method for high-plex spatial analysis of proteins and RNA in tissue, and demonstrates its application in studying immune and cancer microenvironments.

bioRxiv · Feb 26, 2019 · PreprintPathology