Author

K. H. Xu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Organism:non-human primate· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

J. D. Pirl· 2 shared K. Pelka· 2 shared L. T. Nieman· 2 shared M. Hofree· 2 shared S. Sarkizova· 2 shared V. Jorgji· 2 shared A. Bejnood· 1 shared A. K. Coley· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

J. D. Pirl

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Porcine Skin Microbiome Exhibits Broad Fungal Antagonism

K. F. De La Cruz, E. C. Townsend, J. A. Cheong, R. Salamzade, A. Liu, S. Sandstrom, E. Davila, L. Huang, K. H. Xu, S. Y. Wu, J. J. Meudt, D. Shanmuganayagam, A. L. Gibson, L. R. Kalan

This study characterizes the porcine skin microbiome, identifies antifungal bacterial isolates, and discovers novel fungal and bacterial species with potential for antifungal applications.

bioRxiv · Jan 12, 2024 · PreprintMicrobiology

Single Cell Spatial Transcriptomic Profiling Identifies a LINE1 Associated Disarrayed Immune Microenvironment in Hepatocellular Carcinoma

A. K. Coley, C. Nawrocki, B. K. Patel, A. Pankaj, Z. Guo, M. J. Emmett, E. R. Lang, Y. Song, K. H. Xu, C. R. Ferrone, V. Deshpande, L. T. Nieman, M. Aryee, J. W. Franses, D. T. Ting

This study uses single cell spatial transcriptomics to show LINE1 repeat RNA expression in HCC correlates with a disorganized immune microenvironment and poor patient survival.

bioRxiv · Dec 4, 2023 · PreprintCancer Biology

Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response

J. H. Chen, L. T. Nieman, M. Spurrell, V. Jorgji, P. M. Richieri, K. H. Xu, R. Madhu, M. Parikh, I. Zamora, A. Mehta, C. S. Nabel, S. S. Freeman, J. D. Pirl, C. Lu, C. B. Meador, , N. Hacohen

The paper identifies immune hubs in lung cancer that are associated with better responses to PD-1-blockade immunotherapy and contain stem-like CD8 T cells.

bioRxiv · Apr 4, 2023Immunology

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

K. Pelka, M. Hofree, J. Chen, S. Sarkizova, J. D. Pirl, V. Jorgji, A. Bejnood, D. Dionne, W. H. Ge, K. H. Xu, S. X. Chao, D. R. Zollinger, D. J. Lieb, J. W. Reeves, C. A. Fuhrman, , J

The paper identifies immune hubs in colorectal cancer by analyzing transcriptional and spatial patterns in MMRd and MMRp tumors.

bioRxiv · Jan 30, 2021 · PreprintCancer Biology