Author

D. S. Brewer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. S. Cooper· 3 shared A. Babbage· 1 shared A. Butler· 1 shared A. Chanalaris· 1 shared A. G. Lynch· 1 shared A. Gihawi· 1 shared A. Grundhoff· 1 shared A. Lambert· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCancer Biology

C. S. Cooper

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel Methylation Markers in a Prostate Cancer Cohort are Associated with Disease Development and Relapse

R. P. Lach, S. Pita, W.-K. Leung, A. Babbage, S. Merson, S. Hawkins, H. Luxton, J. Kay, H. C. Whitaker, D. J. Woodcock, V. Haberland, Z. Kote-Jarai, T. Milne-Clark, K. O'Neill, T. Brendler-Spaeth, , A. G. Lynch

The paper identifies novel methylation markers in a prostate cancer cohort associated with disease development and relapse, showing their predictive power for recurrence.

bioRxiv · Aug 27, 2026 · PreprintCancer Biology

The extracellular heparan sulfatase SULF2 limits myeloid IFNbeta signaling and Th17 responses in inflammatory arthritis.

M. Swart, A. Redpath, J. Ogbechi, R. Cardenas, L. Topping, E. B. Compeer, M. Goddard, A. Chanalaris, R. Williams, D. S. Brewer, N. Smart, C. Monaco, L. Troeberg

This study shows that SULF2 limits myeloid IFNβ signaling and Th17 responses in inflammatory arthritis by modulating heparan sulfate remodeling.

bioRxiv · Mar 13, 2024Immunology

Major data analysis errors invalidate cancer microbiome findings

A. Gihawi, Y. Ge, J. Lu, D. Puiu, A. Xu, C. S. Cooper, D. S. Brewer, M. Pertea, S. Salzberg

The paper re-analyzes a cancer microbiome study and identifies two major data and methodological errors that invalidate its findings and those of subsequent studies.

bioRxiv · Jul 28, 2023Cancer Biology

The landscape of viral associations in human cancers

M. Zapatka, I. Borozan, D. S. Brewer, M. Iskar, A. Grundhoff, M. Alawi, N. Desai, H. Sueltmann, H. Moch, PCAWG Pathogens Working Group, ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network, C. S. Cooper, R. Eils, V. Ferretti, P. Lichter

The paper systematically investigates viral associations in human cancers using whole-genome and transcriptome data from 2,656 donors, revealing prevalence of known tumor-associated viruses and their genomic impacts.

bioRxiv · Sep 9, 2019Cancer Biology