N. Desai

Starvation Decreases Immunity and Immune Regulatory Factor NF-κB in the Starlet Sea Anemone Nematostella vectensis

This study shows that starvation reduces immunity and NF-κB activity in the sea anemone Nematostella vectensis, linking nutrition and immune function in a marine invertebrate.

Visualising formation of the ribosomal active site in mitochondria

The paper uses cryo-electron microscopy to visualize mitoribosome biogenesis, showing how GTPBP7 and NSUN4/MTERF4 regulate PTC formation and mitochondrial function.

An automated, high throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma

The paper optimizes an automated high-throughput method for isolating cell-free mitochondrial and nuclear DNA from plasma, achieving 6-fold higher yields of mitochondrial DNA.

The landscape of viral associations in human cancers

The paper systematically investigates viral associations in human cancers using whole-genome and transcriptome data from 2,656 donors, revealing prevalence of known tumor-associated viruses and their genomic impacts.

Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance

This study shows that PIF1 helicase deficiency in female mice on a Western diet leads to increased weight gain but not inflammation or reduced glucose clearance.