Author

D. Sachs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Hansen· 1 shared A. Jacobs· 1 shared A. Ma'ayan· 1 shared A. Park· 1 shared B. Lee· 1 shared B. Nilsson-Payant· 1 shared B. R. tenOever· 1 shared B. Shewale· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Hansen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

N. M. Wickramasinghe, D. Sachs, B. Shewale, D. M. Gonzalez, P. Dhanan-Krishnan, D. Torre, E. LaMarca, S. Raimo, R. Dariolli, M. Serasinghe, J. Mayourian, R. Sebra, K. G. Beaumont, R. Iyengar, D. L. French, , N. C. Dubois

This study shows that activating PPARD signaling enhances metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

bioRxiv · Jul 12, 2021 · PreprintCell Biology

Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity

S. Ikegame, S. M. Beaty, C. Stevens, T. S. Won, A. Park, D. Sachs, P. Hong, P. A. Thibault, B. Lee

This study uses transposon mutagenesis to analyze genomic plasticity in paramyxoviruses, finding structural constraints in envelope glycoproteins and variability in genomic regions.

bioRxiv · Mar 30, 2020Microbiology

SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems

D. Blanco-Melo, B. Nilsson-Payant, W.-C. Liu, R. Moeller, M. Panis, D. Sachs, R. Albrecht, B. R. tenOever

This study characterizes the host transcriptional response to SARS-CoV-2 and other respiratory viruses in multiple models, finding a unique muted response lacking certain cytokine and chemokine induction.

bioRxiv · Mar 24, 2020Microbiology