Author

R. Dariolli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. Biagi· 3 shared C. d. S. G. Pedrosa· 2 shared C. Q. Sacramento· 2 shared C. Verissimo· 2 shared D. R. Furtado· 2 shared E. Cruvinel· 2 shared G. Vitoria· 2 shared H. L. Borges· 2 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

D. Biagi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

N. M. Wickramasinghe, D. Sachs, B. Shewale, D. M. Gonzalez, P. Dhanan-Krishnan, D. Torre, E. LaMarca, S. Raimo, R. Dariolli, M. Serasinghe, J. Mayourian, R. Sebra, K. G. Beaumont, R. Iyengar, D. L. French, , N. C. Dubois

This study shows that activating PPARD signaling enhances metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

bioRxiv · Jul 12, 2021 · PreprintCell Biology

In situ maturated early-stage human induced pluripotent stem cell-derived cardiomyocytes improve cardiac function by enhancing segmentary contraction in infarcted rats

D. Biagi, E. T. Fantozzi, J. C. Campos-Oliveira, M. V. Naghetini, A. F. Ribeiro, S. Rodrigues, I. Ogusuku, R. Vanderlinde, M. L. A. Christie, D. B. Mello, A. C. Campos de Carvalho, M. Valadares, E. Cruvinel, R. Dariolli

bioRxiv · Mar 9, 2021Physiology

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2

L. G. H. S. Aragao, J. T. Oliveira, J. R. Temerozo, M. A. Mendes, J. A. Salerno, C. d. S. G. Pedrosa, T. Puig-Pijuan, C. Verissimo, I. M. Ornelas, T. Torquato, G. Vitoria, C. Q. Sacramento, N. Fintelman-Rodrigues, S. d. S. G. Dias, V. Cardoso Soares, , S. Rehen

This study examines the effects of the cannabinoid agonist WIN 55,212-2 on inflammation and cell survival in human iPSC-derived cardiomyocytes infected with SARS-CoV-2, finding reduced cytokine levels and cytotoxic damage.

bioRxiv · Feb 20, 2021 · PreprintCell Biology

Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

J. A. Salerno, T. Torquato, J. R. Temerozo, L. Goto-Silva, M. A. Mendes, C. Q. Sacramento, N. Fintelman-Rodrigues, G. Vitoria, L. R. Q. Souza, I. M. Ornelas, C. Verissimo, K. Karmirian, C. d. S. G. Pedrosa, S. d. S. G. Dias, V. C. Soares, , S. Rehen

This study shows that inhibiting the Sigma-1 receptor with NE-100 reduces SARS-CoV-2 infection in human cardiomyocytes but also impairs cytoskeleton and contractility.

bioRxiv · Feb 20, 2021 · PreprintCell Biology

Long-term single-cell passaging of human iPSC fully supports pluripotency and high-efficient trilineage differentiation capacity

E. Cruvinel, I. Ogusuku, R. Cerioni, J. Goncalves, M. E. Goes, A. C. Silva, J. Alvim, A. Pereira, R. Dariolli, M. Valadares, D. G. Biagi

This study validates a long-term single-cell passaging method for human iPSC that maintains pluripotency and efficient trilineage differentiation.

bioRxiv · Apr 8, 2020Cell Biology