Author

D. T. Egu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Waschke· 2 shared S. Kotschi· 2 shared A. Bartelt· 1 shared A. M. Sigmund· 1 shared A. Mena Gomez· 1 shared A. S. Yazdi· 1 shared C. Jethwa· 1 shared D. Kugelmann· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

J. Waschke

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Author profile →

2 papers

Recent·Most cited

The myocyte Nfe2l1-ubiquitin-proteasome system controls muscle fiber type and obesity-induced insulin resistance

I. L. Lemmer, D. T. Haas, N. Willemsen, S. Kotschi, I. Toksoez, E. Gjika, S. Khani, M. Rohm, N. Diercksen, P. B. H. Nguyen, M. P. Menden, D. T. Egu, J. Waschke, S. Larsen, T. Ma, , A. Mena Gomez

This study shows that Nfe2l1 regulates skeletal muscle proteostasis and function, with its loss causing muscle fiber type switching and insulin resistance in high-fat diet conditions.

bioRxiv · Apr 20, 2023 · PreprintPhysiology

Apremilast prevents blistering in human epidermis by stabilization of keratinocyte adhesion in pemphigus.

A. M. Sigmund, M. Winkler, S. Engelmayer, D. T. Egu, D. Kugelmann, M. Y. Radeva, F. C. Bayerbach, S. Kotschi, S. Yeruva, E. Schmidt, A. S. Yazdi, K. Ghoreschi, F. Vielmuth, J. Waschke

This study shows apremilast stabilizes keratinocyte adhesion in pemphigus by phosphorylating plakoglobin at serine 665, preventing blistering without affecting desmoglein depletion or binding.

bioRxiv · Feb 7, 2022Cell Biology