Author

N. Willemsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Bartelt· 3 shared S. Kotschi· 2 shared A. Jung· 1 shared A. Mena Gomez· 1 shared A. Ofoghi· 1 shared B. Proneth· 1 shared C. Jethwa· 1 shared D. T. Egu· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersPhysiology

A. Bartelt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The myocyte Nfe2l1-ubiquitin-proteasome system controls muscle fiber type and obesity-induced insulin resistance

I. L. Lemmer, D. T. Haas, N. Willemsen, S. Kotschi, I. Toksoez, E. Gjika, S. Khani, M. Rohm, N. Diercksen, P. B. H. Nguyen, M. P. Menden, D. T. Egu, J. Waschke, S. Larsen, T. Ma, , A. Mena Gomez

This study shows that Nfe2l1 regulates skeletal muscle proteostasis and function, with its loss causing muscle fiber type switching and insulin resistance in high-fat diet conditions.

bioRxiv · Apr 20, 2023 · PreprintPhysiology

Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

N. Willemsen, I. Arigoni, M. Studencka-Turski, E. Krüger, A. Bartelt

This study shows that proteasome subunit PSMB4 is critical for brown adipocyte differentiation and function, with its loss causing inflammation and adipogenesis disruption via ATF3 activation.

bioRxiv · Jan 14, 2022Pathology

NFE2L1-mediated proteasome function protects from ferroptosis

S. Kotschi, A. Jung, N. Willemsen, A. Ofoghi, B. Proneth, M. Conrad, A. Bartelt

This study identifies NFE2L1 as a regulator of proteasome function that protects cells from ferroptosis, with implications for cancer and neurodegenerative diseases.

bioRxiv · Dec 12, 2021Biochemistry