Author

D. Tilakawardane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. K. Park· 2 shared S. J. Forman· 2 shared S. J. Priceman· 2 shared A. M. Wu· 1 shared B. J. Gittins· 1 shared B. Jeang· 1 shared C. Martinez· 1 shared C. P. Tran· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

A. K. Park

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pre-conditioning Modifies the Tumor Microenvironment to Enhance Solid Tumor CAR T Cell Efficacy and Endogenous Immunity

J. P. Murad, D. Tilakawardane, A. K. Park, K. T. Kennewick, L. S. Lopez, H. J. Lee, B. J. Gittins, W.-C. Chang, C. P. Tran, C. Martinez, A. M. Wu, R. E. Reiter, T. B. Dorff, S. J. Forman, S. J. Priceman

This study shows that cyclophosphamide pre-conditioning improves CAR T cell efficacy against solid tumors by modifying the immunosuppressive tumor microenvironment without harming normal tissues.

bioRxiv · Nov 18, 2020Immunology

Effective Combination Immunotherapy using Oncolytic Viruses to Deliver CAR Targets to Solid Tumors

A. K. Park, Y. Fong, N. Chen, B. Jeang, D. Tilakawardane, J. Murad, S. I. Kim, J. Lu, S. Thomas, S. J. Forman, S. J. Priceman

This study combines oncolytic viruses with CAR T cells to deliver CD19 antigen to solid tumors, enhancing CAR T cell anti-tumor responses.

bioRxiv · Nov 16, 2019Cancer Biology