Author

J. P. Murad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Martinez· 2 shared S. J. Forman· 2 shared S. J. Priceman· 2 shared W.-C. Chang· 2 shared A. K. Park· 1 shared A. M. Wu· 1 shared A. Park· 1 shared B. Gittins· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Martinez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting

E. Lee, C. Cullen, J. P. Murad, D. Gumber, A. Park, J. Yang, L. Stern, L. Adkins, G. Dhapola, B. Gittins, W.-C. Chang, C. Martinez, Y. Woo, M. Cristea, L. Rodriguez, , S. J. Priceman

This study develops TAG72-CAR T cells with antigen-dependent IL-12 signaling to enhance anti-tumor activity and systemic disease targeting in ovarian cancer.

bioRxiv · Jan 6, 2023 · PreprintCancer Biology

Pre-conditioning Modifies the Tumor Microenvironment to Enhance Solid Tumor CAR T Cell Efficacy and Endogenous Immunity

J. P. Murad, D. Tilakawardane, A. K. Park, K. T. Kennewick, L. S. Lopez, H. J. Lee, B. J. Gittins, W.-C. Chang, C. P. Tran, C. Martinez, A. M. Wu, R. E. Reiter, T. B. Dorff, S. J. Forman, S. J. Priceman

This study shows that cyclophosphamide pre-conditioning improves CAR T cell efficacy against solid tumors by modifying the immunosuppressive tumor microenvironment without harming normal tissues.

bioRxiv · Nov 18, 2020Immunology