Author

D. X. Dobbins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

S. Shiva· 2 shared A. Burch· 1 shared A. D'Souza· 1 shared A. Sreeram· 1 shared A. Sullivan· 1 shared C. Sabatelle· 1 shared D. B. Stolz· 1 shared D. S Manickam· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

S. Shiva

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mitochondria-containing EVs Protect Brain Endothelial Cells and Reduce Mouse Brain Infarct Sizes

K. Dave, D. B. Stolz, V. R. Venna, V. A. Quaicoe, M. E. Maniskas, M. J. Reynolds, R. Babidhan, D. X. Dobbins, M. N. Farinelli, A. Sullivan, T. N. Bhatia, H. Yankello, R. Reddy, Y. Bae, R. K. Leak, , D. Soundara Manickam

This paper shows that medium-to-large extracellular vesicles (m/lEVs) protect brain endothelial cells by transferring mitochondria and reducing brain infarct sizes in a mouse stroke model.

bioRxiv · Oct 29, 2021Bioengineering

Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells

A. D'Souza, A. Burch, K. M. Dave, A. Sreeram, M. S. Reynolds, D. X. Dobbins, Y. S. Kamte, W. Zhao, C. Sabatelle, G. M. Joy, V. Soman, U. R. Chandran, S. Shiva, N. Quillinan, P. S. Herson, D. S Manickam

This paper shows that microvesicles transfer mitochondria to brain endothelial cells and neurons, increasing ATP levels under ischemic conditions, while exosomes do not affect mitochondrial function.

bioRxiv · Apr 10, 2021Bioengineering