Author

Daniel Kahne

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrew C. KruseiD· 2 shared Amanda K. WilliamsoniD· 1 shared Chérine BecharaiD· 1 shared Ethan Garner· 1 shared Georgia Squyres· 1 shared Hongbaek Cho· 1 shared Jackson Buss· 1 shared James Osei‐OwusuiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Andrew C. KruseORCID

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2 papers

Recent·Most cited

Divergent activation of the RXFP1 relaxin receptor by protein and small molecule agonists

James Osei‐Owusu, Tristan Girbau, Xunan Wang, Jeffrey S. Smith, Pengxiang Shen, Sarah C. Erlandson, Amanda K. Williamson, Xiaojing Cong, Mark W. Grinstaff, Daniel Kahne, Chérine Bechara, Andrew C. Kruse

This study presents cryo-EM structures of RXFP1 bound to relaxin-2 and AZD5462, revealing distinct activation mechanisms for protein and small-molecule agonists.

bioRxiv · Jun 11, 2026 · PreprintBiochemistry

An activation pathway governs cell wall polymerization by a bacterial morphogenic machine

Patricia D. A. Rohs, Jackson Buss, Sue Sim, Georgia Squyres, Veerasak Srisuknimit, Mandy Smith, Hongbaek Cho, Megan Sjodt, Andrew C. Kruse, Ethan Garner, Suzanne Walker, Daniel Kahne, Thomas G. Bernhardt

The paper identifies an activation pathway involving PBP2 that enhances cell wall polymerization and MreB filament formation in E. coli.

bioRxiv · Jun 29, 2018 · PreprintMicrobiology