Recruitment of Fpt1 to tRNA genes requires TFIIIB and the N-terminal TPR array of TFIIIC subunit {tau}131
Maria Elize van Breugel, Wolfram Seifert-Dávila, Morten P. Bakker, Joseph V.W. Meeussen, Ilse A. Hoogvliet, Mireia Novell Cardona, Tibor van Welsem, Danique Ammerlaan, Florence Baudin, Patrick H. N. Celie, Tineke Laura Lenstra, Christoph W. Müller, Fred van Leeuwen
The paper investigates how Fpt1 is recruited to tRNA genes in budding yeast, revealing a dual role of TFIIIB and TFIIIC in its binding under different RNAPIII conditions.
bioRxiv · Dec 26, 2025 · PreprintMolecular Biology