Author

David I.H. Jee

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Eric C. LaiiD· 2 shared Adrienne SamaniiD· 1 shared Andrea L. ReidiD· 1 shared Danwei HuangfuiD· 1 shared Dapeng YangiD· 1 shared David Alan SchneideriD· 1 shared David K. CrossmaniD· 1 shared J. Scott Doyle· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Eric C. LaiORCID

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2 papers

Recent·Most cited

Human Dicer1 hotspot mutation induces both loss and gain of miRNA function

David I.H. Jee, Seungjae Lee, Dapeng Yang, Robert W. Rickert, Renfu Shang, Danwei Huangfu, Eric C. Lai

This study investigates the effects of a Dicer1 mutation on miRNA function, showing both loss and gain of miRNA activity through strand switching.

Nature Structural & Molecular Biology · Nov 4, 2025Peer-reviewedBiochemistry

miR-486 is an epigenetic modulator of Duchenne muscular dystrophy pathologies

Rylie M. Hightower, Adrienne Samani, Andrea L. Reid, Katherine G. English, Michael A. Lopez, J. Scott Doyle, Michael J. Conklin, David Alan Schneider, Marcas M. Bamman, Jeffrey J. Widrick, David K. Crossman, Min Xie, David I.H. Jee, Eric C. Lai, Matthew S. Alexander

The paper shows miR-486 is reduced in DMD muscles and its loss causes muscle and cardiac defects, identifying it as a driver of disease and a potential biomarker.

bioRxiv · Jun 14, 2021 · PreprintGenetics