Seungjae Lee

Alternative 3' Polyadenylation Responses to Acute Ethanol Exposure Differ Between Drosophila Populations

The paper identifies population-specific alternative polyadenylation (APA) responses to acute ethanol exposure in Drosophila melanogaster, showing genotype- and population-dependent shifts in 3' UTR length.

Human Dicer1 hotspot mutation induces both loss and gain of miRNA function

This study investigates the effects of a Dicer1 mutation on miRNA function, showing both loss and gain of miRNA activity through strand switching.

Separable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance

The paper investigates the roles of Microprocessor and its cofactors ERH and SAFB1/2 in miRNA cluster assistance, revealing their distinct functional contributions to the process.

Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution

The paper presents an aging Drosophila cell atlas, identifies cell type-specific aging patterns, and shows ribosomal gene expression as a conserved aging predictor.

Overlapping activities of ELAV/Hu RNA binding proteins specify multiple neural alternative splicing programs

This study investigates the roles of ELAV/Hu RNA binding proteins in neuronal alternative splicing and polyadenylation, showing their overlapping functions in suppressing exons and polyadenylation sites.