A systems view of spliceosomal assembly and branchpoints with iCLIP
Michael Briese, Nejc Haberman, Christopher R. Sibley, Rupert Faraway, Andrea S. Elser, Anob M. Chakrabarti, Zhen Wang, Julian König, David Perera, Vihandha O. Wickramasinghe, Ashok R. Venkitaraman, Nicholas M. Luscombe, Luciano Saieva, Livio Pellizzoni, Christopher W. J. Smith, , Jernej Ule
The paper uses spliceosome iCLIP to map human spliceosome engagement with snRNAs and pre-mRNAs, identifying over 50,000 branchpoints and their associated splicing factor binding patterns.
Nature Structural & Molecular Biology · Sep 30, 2019Peer-reviewedGenomics