Author

Deborah Duran

Hadassah Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Myriam GrunewaldiD· 4 shared Liron Birimberg‐SchwartziD· 2 shared Amal Gharbi· 1 shared Amandeep SinghiD· 1 shared Arun Kumar SharmaiD· 1 shared Aryeh M. Weiss· 1 shared Avital Sarusi-PortugueziD· 1 shared Aviya Habshush MenachemiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersImmunology

Myriam GrunewaldORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TLR2-mediated microbial sensing by intestinal stem cells coordinates epithelial antimicrobial defense.

Aviya Habshush Menachem, Sacha Lebon, Christoph Killian, V. V. Holiar, Avital Sarusi-Portuguez, Natalia Davidzohn, Barak Toval, Carmel Sochen, Smadar Levin‐Zaidman, Nili Dezorella, Leilah Otikovs, Deborah Duran, Ilan Kent, Myriam Grunewald, Lorenz Adlung, Moshe Biton

This study shows intestinal stem cells use TLR2 to sense microbes, coordinating epithelial defense and regeneration.

bioRxiv · May 7, 2026 · PreprintImmunology

AVJ16 inhibits the RNA binding protein IGF2BP1 in lung adenocarcinomas and prevents tumor growth in mice

Nadav Wallis, Tehila Gershon, Sojod Shaaby, Froma Oberman, Myriam Grunewald, Deborah Duran, Amandeep Singh, Gilad Wolf Vainer, Vladimir S. Spiegelman, Arun Kumar Sharma, Joel K. Yisraeli

AVJ16 inhibits IGF2BP1 in lung adenocarcinoma cells and xenografts, reducing proliferation, enhancing apoptosis, and preventing tumor growth.

Oncogene · Jul 8, 2025Peer-reviewedCancer Biology

Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro

Marco Canella, Amal Gharbi, Deborah Duran, Noa Corem, Yinon Ben‐Neriah, Liron Birimberg‐Schwartz, Ittai Ben‐Porath, Myriam Grunewald, Michal Shoshkes-Carmel

This paper establishes an immortalized intestinal telocyte cell line that supports stem cell organoid growth in co-culture, demonstrating telocytes' sufficiency in maintaining stem cell activity.

bioRxiv · Nov 27, 2024 · PreprintCell Biology

CFTR structures bound to ETI components predict rare mutation response to modulator combinations

Noemie Stanleigh, Michal Gur, Michal Shteinberg, Aryeh M. Weiss, Naama Sebbag-Sznajder, Deborah Duran, Myriam Grunewald, Liron Birimberg‐Schwartz, Ronen Bar‐Yoseph, Jeffrey Matthijn Beekman, Eitan Kerem, Michael A. Wilschanski, Batsheva Kerem

The paper predicts and validates responses to CFTR modulator combinations in patients with rare mutations using structural data and functional assays.

medRxiv · Oct 12, 2024 · PreprintGenetic & Genomic Medicine