Despina Stamataki

This study identifies Bro1 as a central integrator linking TOR signalling to metabolic adaptation and longevity in fission yeast.

The paper compares protein dynamics in mouse and human neural progenitors, finding that human NPs have longer protein half-lives and lower proteasomal activity, which influences developmental tempo.

The paper identifies spatial and molecular differences in cardiac progenitor origins in mouse embryos, showing distinct regions of the primitive streak contribute to different heart structures.

The paper shows that slower human embryonic development compared to mice is due to higher protein stability and longer cell cycle duration in human cells.

The paper challenges the established model of neural induction by showing that cells commit to anterior or posterior regional identities before acquiring neural identity.