Author

Douglas Dunn

Altius Institute for Biomedical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Organism:mouse· 1

Frequent Co-Authors

Daniel BatesiD· 4 shared John A. StamatoyannopoulosiD· 4 shared Richard S. SandstromiD· 4 shared Alex P. ReynoldsiD· 3 shared Eric HaugeniD· 3 shared Eric RynesiD· 3 shared Fidencio Jun Neri· 3 shared Jessica M. Halow· 3 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Daniel BatesORCID

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Author profile →

4 papers

Recent·Most cited

Index and biological spectrum of accessible DNA elements in the human genome

Wouter R. A. Meuleman, Alexander Muratov, Eric Rynes, Jessica M. Halow, Kristen Lee, Daniel Bates, Morgan Diegel, Douglas Dunn, Fidencio Jun Neri, Athanasios Teodosiadis, Alex P. Reynolds, Eric Haugen, Jemma S. Nelson, Audra Johnson, Mark Frerker, , John A. Stamatoyannopoulos

The paper creates high-precision maps of DNase I hypersensitive sites across 733 human biosamples and develops a regulatory vocabulary to annotate regulatory DNA, concentrating disease-associated signals.

Nature · Jul 29, 2020Peer-reviewedGenomics

Global reference mapping and dynamics of human transcription factor footprints

Jeff D. Vierstra, John E. Lazar, Richard S. Sandstrom, Jessica M. Halow, Kristen Lee, Daniel Bates, Morgan Diegel, Douglas Dunn, Fidencio Jun Neri, Eric Haugen, Eric Rynes, Alex P. Reynolds, Jemma S. Nelson, Audra Johnson, Mark Frerker, , John A. Stamatoyannopoulos

The paper maps transcription factor footprints across 243 human cell and tissue types, revealing their structure, function, and relationship to genetic variation and disease.

Nature · Jul 29, 2020Peer-reviewedGenomics

Atlas and developmental dynamics of mouse DNase I hypersensitive sites

Charles E. Breeze, John E. Lazar, Tim R. Mercer, Jessica M. Halow, Ida W. Smoak, Kristen Lee, Sean Ibarrientos, Andrés Castillo, Fidencio Jun Neri, Eric Haugen, Eric Rynes, Alex P. Reynolds, Daniel Bates, Morgan Diegel, Douglas Dunn, , John A. Stamatoyannopoulos

The paper creates a mouse regulatory DNA atlas by mapping DNase I hypersensitive sites across development and shows dynamic changes in regulatory elements and transcription factor activity.

bioRxiv · Jun 26, 2020 · PreprintGenomics

Quantitative dialing of gene expression via precision targeting of KRAB repressor

Matthew S. Wilken, Christie Ciarlo, Jocelynn R. Pearl, Elaine V. Schanzer, Hanna Liao, Benjamin P. Van Biber, Konstantin Queitsch, Jordan E. Bloom, Alexander Joel Federation, Reyes Acosta, Shinny Vong, Ericka Otterman, Douglas Dunn, Hao Wang, Pavel Zrazhevskiy, , John A. Stamatoyannopoulos

This study demonstrates precise control of gene expression levels by targeting the KRAB repressor domain in human cells.

bioRxiv · Feb 19, 2020 · PreprintSynthetic Biology