Author

E. B. Snaar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Groenewoud· 2 shared G. Zhao· 2 shared J. Yin· 2 shared L. Chen· 2 shared F. B. Engel· 1 shared G. E. M. Lamers· 1 shared G. Forn-Cuni· 1 shared G. N. Thalmann· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Groenewoud

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechano-signaling of prostate tumor initiating cells facilitates their tropism to stiff metastatic niche

L. Chen, G. Zhao, M. De Menna, S. Coppola, A. Groenewoud, N. Landman, S. Schieven, G. N. Thalmann, T. Schmidt, J. de Vrie, M. Kruithof-de Julio, E. B. Snaar

The paper shows that mechanotransduction via TAZ and cytoskeletal tension promotes prostate cancer stem cell metastasis and identifies a YAP/TAZ inhibitor as a potential therapeutic target.

bioRxiv · Aug 28, 2023 · PreprintCancer Biology

Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer

G. Zhao, G. Forn-Cuni, M. Scheers, P. P. Lindenbergh, J. Yin, Q. van Loosen, L. Passarini, L. Chen, E. B. Snaar

This study shows that targeting both AMPK and mTOR can inhibit prostate cancer metastasis by blocking the metabolic switch required for tumor growth in new environments.

bioRxiv · Aug 14, 2023Cancer Biology

Melanin enhances metastatic melanoma colonization by inhibiting ferroptosis

A. Groenewoud, G. Zhou, M. C. Gelmi, J. Yin, G. E. M. Lamers, R. van Doorn, R. M. Verdijk, M. J. Jager, F. B. Engel, E. B. Snaar

This study shows melanin protects melanoma cells from ferroptosis, enhancing metastasis, and suggests targeting melanin and ferroptosis could improve treatment of metastatic melanoma.

bioRxiv · Apr 3, 2023 · PreprintCancer Biology