Melanin enhances metastatic melanoma colonization by inhibiting ferroptosis
A. Groenewoud, G. Zhou, M. C. Gelmi, J. Yin, G. E. M. Lamers, R. van Doorn, R. M. Verdijk, M. J. Jager, F. B. Engel, E. B. Snaar
This study shows melanin protects melanoma cells from ferroptosis, enhancing metastasis, and suggests targeting melanin and ferroptosis could improve treatment of metastatic melanoma.
bioRxiv · Apr 3, 2023 · PreprintCancer Biology