Author

M. C. Gelmi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:zebrafish· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. J. Jager· 3 shared A. G. Jochemsen· 2 shared A. Groenewoud· 2 shared J. Yin· 2 shared A. C. O. Vertegaal· 1 shared A. F. A. S. Teunisse· 1 shared D. Decaudin· 1 shared E. B. Snaar· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

M. J. Jager

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Author profile →

3 papers

Recent·Most cited

Comparative phosphoproteome analysis of primary and metastatic uveal melanoma cell lines

K. Glinkina, R. G. Prieto, A. F. A. S. Teunisse, M. C. Gelmi, M. J. Jager, A. C. O. Vertegaal, A. G. Jochemsen

The paper compares phosphoproteomes of primary and metastatic uveal melanoma cell lines to identify altered signaling pathways and potential drug targets.

bioRxiv · Dec 6, 2023 · PreprintCancer Biology

Melanin enhances metastatic melanoma colonization by inhibiting ferroptosis

A. Groenewoud, G. Zhou, M. C. Gelmi, J. Yin, G. E. M. Lamers, R. van Doorn, R. M. Verdijk, M. J. Jager, F. B. Engel, E. B. Snaar

This study shows melanin protects melanoma cells from ferroptosis, enhancing metastasis, and suggests targeting melanin and ferroptosis could improve treatment of metastatic melanoma.

bioRxiv · Apr 3, 2023 · PreprintCancer Biology

Patient-derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma

A. Groenewoud, J. Yin, M. C. Gelmi, S. Alsafadi, F. Nemati, D. Decaudin, S. Roman-Roman, H. Kalirai, S. E. Coupland, A. G. Jochemsen, M. J. Jager, E. Snaar-Jagalska

The paper develops a zebrafish xenograft model of metastatic uveal melanoma and identifies ferroptosis as a druggable vulnerability in tumors with BAP1 loss.

bioRxiv · Oct 26, 2021 · PreprintCancer Biology