Author

E. F. Merino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:plant (other)· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:virus· 1

Frequent Co-Authors

M. B. Cassera· 3 shared A. L. Valenciano· 2 shared M. L. Fernandez-Murga· 2 shared N. R. Holderman· 2 shared A. Botnar· 1 shared A. Florentin· 1 shared A. Vantaux· 1 shared B. Witkowski· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

M. B. Cassera

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Alkyne modified purines for assessing activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.

A. Botnar, G. Lawrence, S. P. Maher, A. Vantaux, B. Witkowski, J. C. Shiau, E. F. Merino, D. De Vore, C. Yang, C. Murray, M. B. Cassera, J. W. Leahy, D. E. Kyle

This study develops alkyne-modified purines as a DNA synthesis marker to distinguish replicating and non-replicating Plasmodium stages, aiding in understanding dormancy mechanisms.

bioRxiv · Oct 12, 2021 · PreprintMicrobiology

Metabolomics profiling reveals new aspects of dolichol biosynthesis in Plasmodium falciparum

F. M. Zimbres, A. L. Valenciano, E. F. Merino, N. R. Holderman, A. Florentin, G. He, K. Gawarecka, K. Skorupinska-Tudek, M. L. Fernandez-Murga, E. Swiezewska, X. Wang, V. Muralidharan, M. B. Cassera

This study uses metabolomics to show that Plasmodium falciparum has diverse and active cis-polyisoprenoid biosynthesis, including polyprenols and dolichols, with functional substitution potential.

bioRxiv · Mar 18, 2020Biochemistry

Metabolic dependency of chorismate in Plasmodium falciparum

A. L. Valenciano, M. L. Fernandez-Murga, E. F. Merino, N. R. Holderman, G. J. Butschek, K. J. Shaffer, P. C. Tyler, M. B. Cassera

The paper investigates the metabolic dependency of chorismate in Plasmodium falciparum, focusing on ubiquinone biosynthesis and the mechanism of action of MMV688345.

bioRxiv · Jul 13, 2019 · PreprintBiochemistry