J. C. Shiau

Oviposition status and sugar availability influence measures of transmission potential in malaria-infected mosquitoes.

This study shows that oviposition status and sugar availability affect malaria parasite transmission potential in mosquitoes.

Blood meals from 'dead-end' vertebrate hosts enhance transmission potential of malaria-infected mosquitoes

The paper shows that additional blood meals from bovine and canine hosts can enhance sporozoite migration in malaria-infected mosquitoes, with human and bovine blood showing more consistent reductions in extrinsic incubation period.

Alkyne modified purines for assessing activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.

This study develops alkyne-modified purines as a DNA synthesis marker to distinguish replicating and non-replicating Plasmodium stages, aiding in understanding dormancy mechanisms.

Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver

This study shows that limited Caspase-1 cleavage in hepatocytes reduces pyroptosis and cytokine maturation, impairing malaria control, and that enhancing ASC expression improves immune response.

Field relevant variation in ambient temperature modifies the density-dependent establishment of Plasmodium falciparum in mosquitoes: implications for the infectious reservoir and beyond?

This study shows that ambient temperature variation affects Plasmodium falciparum establishment in mosquitoes, with higher temperatures reducing infection rates but increasing oocyst intensity, and density-dependent effects varying by temperature.