Author

E. L. Reinherz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Kim· 2 shared T. Walz· 2 shared W. Hwang· 2 shared Y. Wang· 2 shared A. Akitsu· 1 shared C. M. Messier· 1 shared G. Hiotis· 1 shared H. Richter· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

M. Kim

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility

K. Tan, J. Chen, Y. Kaku, Y. Wang, L. Donius, R. A. Khan, X. Li, H. Richter, M. S. Seaman, T. Walz, W. Hwang, E. L. Reinherz, M. Kim

The paper shows that HIV-1 MPER-targeting antibodies generated by vaccines lack structural constraints needed to access the MPER, despite having bnAb-like paratopes.

bioRxiv · Jun 27, 2023Immunology

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

S. Yang, G. Hiotis, Y. Wang, J. Chen, J.-h. Wang, M. Kim, E. L. Reinherz, T. Walz

The paper investigates HIV-1 spike protein dynamics using cryo-EM and simulations, showing how tilting exposes the MPER to antibody attack and alters membrane fusion.

bioRxiv · May 9, 2022Biophysics

Pre-T cell receptor Self-MHC Sampling Restricts Thymocyte Dedifferentiation

J. S. Duke-Cohan, A. Akitsu, R. J. Mallis, C. M. Messier, P. H. Lizotte, W. Hwang, M. J. Lang, E. L. Reinherz

The paper shows that preTCR-pMHC interactions prevent thymocyte dedifferentiation by analyzing single-cell transcriptomes in fetal thymic cultures with and without pMHC.

bioRxiv · Apr 28, 2022Immunology