Author

E. M. Busch-Nentwich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

L. Ramakrishnan· 2 shared A. Danoff· 1 shared A. J. Pagan· 1 shared C. B. Moens· 1 shared D. M. Tobin· 1 shared E. L. Pearce· 1 shared F. J. Roca· 1 shared J. Edwards-Hicks· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

L. Ramakrishnan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gaucher Disease Protects Against Tuberculosis

J. Fan, V. L. Halre, L. T. Lelieveld, L. J. Whitworth, E. M. Busch-Nentwich, M. Troll, P. H. Edelstein, T. M. Cox, F. J. Roca, J. M. F. G. Aerts, L. Ramakrishnan

This paper shows that the GBA1 N370S mutation, common in Ashkenazi Jews, protects against tuberculosis by enhancing macrophage microbicidal activity through glucosylsphingosine.

bioRxiv · Oct 16, 2022Microbiology

mTOR-regulated Mitochondrial Metabolism Limits Mycobacterium-induced Cytotoxicity

A. J. Pagan, L. J. Lee, J. Edwards-Hicks, C. B. Moens, D. M. Tobin, E. M. Busch-Nentwich, E. L. Pearce, L. Ramakrishnan

This study identifies mTOR as a host factor that protects macrophages from Mycobacterium-induced death by regulating mitochondrial metabolism.

Cell · Sep 1, 2022Peer-reviewedImmunology

A missense mutation dissociates triglyceride and phospholipid transfer activities in zebrafish and human microsomal triglyceride transfer protein

M. H. Wilson, S. Rajan, A. Danoff, R. J. White, M. R. Hensley, V. H. Quinlivan, J. H. Thierer, E. M. Busch-Nentwich, M. M. Hussain, S. A. Farber

This study identifies a missense mutation in MTP that separates triglyceride and phospholipid transfer activities, suggesting potential for selective therapeutic targeting of triglyceride transfer in dyslipidemia.

bioRxiv · Jul 22, 2019Physiology