Author

E. M. Coyne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Hernandez· 3 shared J. W. Lee· 3 shared S. M. Shin· 3 shared W. J. Ho· 3 shared M. Yarchoan· 2 shared X. Yuan· 2 shared Y. Cho· 2 shared A. Cimino-Matthews· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. Hernandez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells

E. M. Grasset, A. Desphande, J. W. Lee, Y. Cho, S. M. Shin, E. M. Coyne, A. Hernandez, X. Yuan, A. Cimino-Matthews, A. J. Ewald, W. J. Ho

The paper uses spatial analysis to show metastasis-initiating cancer cells in breast tumors are closely associated with specific macrophage subtypes, suggesting these interactions promote metastasis.

bioRxiv · Mar 15, 2024Cancer Biology

Liver fibrosis uncouples tumor control from survival after multikinase inhibitor immunotherapy in hepatocellular carcinoma

S. Morita, T. Ando, H. Kikuchi, A. Morita, T. Kobayashi, G. Birch, R. Tanaka, A. Matsui, Z. Ruan, P. Huang, Y. Cho, A. Hernandez, J. W. Lee, E. M. Coyne, S. M. Shin, , D. G. Duda

Liver fibrosis limits the survival benefit of multikinase inhibitor immunotherapy in hepatocellular carcinoma by promoting innate immune-mediated hepatotoxicity despite preserved tumor control.

bioRxiv · Oct 20, 2023 · PreprintCancer Biology

Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade

D. H. Shu, W. J. Ho, L. T. Kagohara, A. Girgis, S. M. Shin, L. Danilova, J. W. Lee, D. N. Sidiropoulos, S. Mitchell, K. Munjal, K. Howe, K. J. Bendinelli, H. Qi, G. Mo, J. Montagne, , M. Yarchoan

This study examines TLS in HCC treated with neoadjuvant immunotherapy, finding TLS correlate with better outcomes and show distinct morphological and functional features in tumor regression.

bioRxiv · Oct 16, 2023 · PreprintImmunology