Author

E. M. Garcia-Cuesta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

M. Mellado· 2 shared A. Garcia-Rubia· 1 shared A. Leibar· 1 shared A. Linares· 1 shared A. M. Gomez Pozo· 1 shared A. Martinez· 1 shared A. Quijada-Freire· 1 shared B. Soler Palacios· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

M. Mellado

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Author profile →

3 papers

Recent·Most cited

Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain

E. M. Garcia-Cuesta, P. Martinez, K. Selvaraju, G. Ulltjärn, A. M. Gomez Pozo, G. D'Agostino, S. Gardeta, A. Quijada-Freire, P. Blanco Gabella, C. Roca, D. del Hoyo, R. Jimenez-Saiz, A. Garcia-Rubia, B. Soler Palacios, P. Lucas, , M. Mellado

This paper identifies a small molecule that modulates CXCR4 nanoclustering without affecting ligand binding, improving therapeutic potential over existing CXCR4 antagonists.

bioRxiv · Nov 19, 2023Cell Biology

CyTOF analysis identifies unusual immune cells in urine of BCG-treated bladder cancer patients

E. Castellano, C. Samba, G. Esteso, L. J. Simpson, E. Vendrame, E. M. Garcia-Cuesta, S. Lopez-Cobo, M. Alvarez-Maestro, A. Linares, A. Leibar, T. Ranganath, H. T. Reyburn, L. Martinez-Pineiro, C. Blish, M. Vales-Gomez

The paper uses CyTOF to identify a novel immune cell population in urine of BCG-treated bladder cancer patients, linking it to inflammatory response and potential treatment risk.

bioRxiv · Jun 12, 2020Immunology

Pre-TCR signaling intensity shapes the TCRβ repertoire

E. R. Bovolenta, E. M. Garcia-Cuesta, J. Ponomarenko, M. Mellado, M. Castro, D. Abia, H. M. van Santen

The paper shows that pre-TCR signaling intensity affects TCRβ repertoire diversity in murine thymocytes by influencing nanoclustering and maturation.

bioRxiv · May 4, 2020 · PreprintImmunology