Author

H. M. van Santen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

M. Castro· 2 shared A. Martin· 1 shared A. Ruiz· 1 shared B. Alarcon· 1 shared C. Drechsler· 1 shared D. Abia· 1 shared E. M. Garcia-Cuesta· 1 shared E. R. Bovolenta· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

M. Castro

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 4, 2020

Pre-TCR signaling intensity shapes the TCRβ repertoire

E. R. Bovolenta, E. M. Garcia-Cuesta, J. Ponomarenko…·H. M. van Santen

The paper shows that pre-TCR signaling intensity affects TCRβ repertoire diversity in murine thymocytes by influencing nanoclustering and maturation.

DOI 10.1101/2020.05.04.074922

𝕏 PostBluesky

ImmunologybioRxivFeb 14, 2020

CCR5 deficiency impairs CD4+ T cell memory responses and antigenic sensitivity through increased ceramide synthesis

A. Martin, R. Blanco, J. Casas…·S. Manes

This study shows that CCR5 deficiency in CD4+ T cells increases ceramide synthesis, reduces TCR nanoclustering, and impairs memory responses and antigenic sensitivity.

DOI 10.15252/embj.2020104749

𝕏 PostBluesky