Author

R. Roozitalab

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. P. McGuigan· 1 shared B. Malacrida· 1 shared E. Maniati· 1 shared F. R. Balkwill· 1 shared J. L. Cadavid· 1 shared L. Lecker· 1 shared M. M. Knight· 1 shared M. Mijalkovic· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

A. P. McGuigan

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Author profile →

2 papers

Recent·Most cited

An off-the-shelf multi-well scaffold-supported platform for tumour organoid-based tissues

N. T. Li, N. C. Wu, R. Cao, J. L. Cadavid, S. Latour, X. Lu, Y. Zhu, M. Mijalkovic, R. Roozitalab, A. P. McGuigan

This paper introduces a high-throughput platform for generating standardized organoid microtissues to enable drug screening and phenotypic assays.

bioRxiv · Aug 14, 2022Bioengineering

Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer

R. Delaine-Smith, E. Maniati, B. Malacrida, S. Nichols, R. Roozitalab, R. R. Jones, L. Lecker, O. M. Pearce, M. M. Knight, F. R. Balkwill

The paper models how TGFβR and Hh pathways regulate ECM molecules in ovarian cancer using tri-culture models and identifies inhibitor combinations that reduce fibroblast activation and ECM remodeling.

bioRxiv · Feb 1, 2021Cancer Biology