Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells
T. Tsuruoka, E. Nakayama, T. Endo, S. Harashima, R. Kamada, K. Sakaguchi, T. Imagawa
This study develops a fluorescence reporter system to visualize endogenous p53 transcriptional activity in living cells, revealing cell-to-cell heterogeneity and cell cycle dependence of p53 activation.
bioRxiv · Aug 3, 2022Cell Biology