T. Yoshikawa

Identification of novel candidate genes associated with the symbiotic compatibility of soybean with rhizobia under natural conditions

This study identifies a novel gene associated with soybean-rhizobia symbiosis through QTL analysis and RNA-seq, potentially improving soybean yield under low nitrogen conditions.

Identification of inosine monophosphate dehydrogenase as a potential target for anti-monkeypox virus agents

This study identifies IMPDH as a potential target for anti-monkeypox virus agents by showing that compounds targeting this enzyme inhibit MPXV replication more effectively than existing treatments.

Potential anti-monkeypox virus activity of atovaquone, mefloquine, and molnupiravir, and their potential use as treatments

This study identifies atovaquone, mefloquine, and molnupiravir as potential anti-monkeypox virus drugs, with atovaquone showing enhanced efficacy when combined with tecovirimat.

Regulation of the plastochron by three MANY-NODED DWARF genes in barley

This study identifies three barley genes regulating the plastochron and leaf growth, showing both conserved and species-specific mechanisms compared to rice.

A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome

This paper develops and tests recombinant vaccinia virus vaccines against SFTS, showing they induce protective immunity and are safe in mice.

Increased serological response against human herpesvirus 6A is associated with risk for multiple sclerosis

The paper investigates the association between serological responses to HHV-6A and HHV-6B and multiple sclerosis risk, finding increased risk with HHV-6A antibodies and interaction with EBV.

Deep learning detects virus presence in cancer histology

This paper uses deep learning to detect the presence of HPV and EBV in cancer histology images, achieving high accuracy in predicting virus-associated tumors.

Characterization of the untranslated region of lymphocytic choriomeningitis virus S segment

This study investigates the functional roles of untranslated regions (UTRs) in the LCMV S segment, revealing their involvement in viral replication, transcription, and virulence, with implications for vaccine development.

Genomic and proteomic analysis of Human herpesvirus 6 reveals distinct clustering of acute versus inherited forms and reannotation of reference strain

This study sequences HHV-6B and iciHHV-6 genomes, identifies geographic clustering and recombination in active infections, and reannotates the HHV-6B genome using transcriptomics and proteomics.