Author

K. Sakaguchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. A. Molinolo· 1 shared A. Goren· 1 shared A. Kock· 1 shared A. Mensenkamp· 1 shared A. Officer· 1 shared B. Sveinbjornsson· 1 shared C. Bartenhagen· 1 shared C. Kanduri· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. A. Molinolo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of novel candidate genes associated with the symbiotic compatibility of soybean with rhizobia under natural conditions

m. teraishi, K. Sakaguchi, T. Tsuchimoto, T. Yoshikawa

This study identifies a novel gene associated with soybean-rhizobia symbiosis through QTL analysis and RNA-seq, potentially improving soybean yield under low nitrogen conditions.

bioRxiv · Apr 4, 2024Plant Biology

YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution

F. Faraji, S. I. Ramirez, L. Clubb, K. Sato, V. Burghi, T. S. Hoang, A. Officer, P. Y. Anguiano Quiroz, W. M. Galloway, Z. Mikulski, K. Medetgul-Ernar, P. Marangoni, K. B. Jones, A. A. Molinolo, K. Kim, , J. S. Gutkind

The paper identifies YAP-driven reprogramming of oral epithelial stem cells into tumor-initiating cells using single-cell multiomics, revealing conserved transcriptional programs linked to poor patient survival.

bioRxiv · Jul 24, 2023Cancer Biology

Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells

T. Tsuruoka, E. Nakayama, T. Endo, S. Harashima, R. Kamada, K. Sakaguchi, T. Imagawa

This study develops a fluorescence reporter system to visualize endogenous p53 transcriptional activity in living cells, revealing cell-to-cell heterogeneity and cell cycle dependence of p53 activation.

bioRxiv · Aug 3, 2022Cell Biology

PPM1D is a neuroblastoma oncogene and therapeutic target in childhood neural tumors.

J. Milosevic, S. Fransson, M. Gulyas, G. Gallo-Oller, T. K. Olsen, D. Treis, M. Wickstrom, L. H. Elfman, B. Sveinbjornsson, F. Hertwig, C. Bartenhagen, S. Reinsbach, M. Wilhelm, F. Abel, N. Javanmardi, , P. Kogner

This study identifies PPM1D as an oncogene and therapeutic target in neuroblastoma by showing its role in p53 inactivation and tumor growth.

bioRxiv · Sep 4, 2020 · PreprintCancer Biology