Author

E. Pellegrini

University of Udine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. von Velsen· 2 shared M. W. Bowler· 2 shared P. Juyoux· 2 shared S. Cusack· 2 shared A. Favier· 1 shared A.-E. Foucher· 1 shared Arianna LodoviciiD· 1 shared B. Brutscher· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

J. von Velsen

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Author profile →

5 papers

Recent·Most cited

Variations in the root-soil system influence the grapevine holobiont by shaping plant physiology and root microbiome

Massimo Guazzini, Ramona Marasco, Radovic S., E. Pellegrini, Marco Vuerich, Arianna Lodovici, Giorgia Dubsky de Wittenau, Eleonora Paparelli, Gabriele Magris, Zanin L., Contin M., De Luca E., Daffonchio D., Gabriele Di Gaspero, Marroni F.

This study shows that soil type and microbial treatments affect grapevine physiology and root microbiome composition, highlighting soil's role in shaping the holobiont.

bioRxiv · Aug 14, 2025Plant Biology

The MAP2Ks can use ADP to phosphorylate and activate their substrate MAPKs in vitro

P. Juyoux, J. von Velsen, E. Pellegrini, M. W. Bowler

The paper shows that MAP2Ks can phosphorylate and activate MAPKs using ADP in vitro, suggesting a potential role in maintaining signaling under ATP-depleted conditions.

bioRxiv · Feb 22, 2024Biochemistry

Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

E. Dubiez, E. Pellegrini, M. Finderup Brask, W. Garland, A.-E. Foucher, K. Huard, T. H. Jensen, S. Cusack, J. Kadlec

The paper reveals how different effectors compete for binding to the CBC-ARS2 complex, influencing RNA fate through structural and biochemical analysis.

bioRxiv · Jul 25, 2023Biochemistry

Structural analysis shows that the BIR2 domain of E3 ligase XIAP binds across the RIP2 kinase dimer interface

M. Lethier, M. Hons, A. Favier, B. Brutscher, E. Boeri Erba, S. Cusack, E. Pellegrini

The paper determines the structure of the RIP2K-XIAP BIR2 complex, revealing its dimeric conformation and molecular mechanisms of interaction.

bioRxiv · Oct 14, 2022Biochemistry

Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation

P. Juyoux, I. Galdadas, D. Gobbo, J. von Velsen, M. Pelosse, M. Tully, O. Vadas, F. L. Gervasio, E. Pellegrini, M. W. Bowler

The paper determines the structure and activation mechanism of the MKK6-p38α complex using cryo-EM and MD simulations, revealing how phosphorylation and interactions drive MAPK specificity.

bioRxiv · Jul 4, 2022Biophysics